. 2018 Aug 30;13(8):e0201892. doi: 10.1371/journal.pone.0201892

Table 2. Summary of simulation under normal errors for naïve, LMEM, SMEMN, SMEM models, respectively.

Naïve	σ_yee		σ_yes						γ_1,ee		γ_2,ee		γ_3,ee		γ_1,es		γ_2,es		γ_3,es
Replicates	2	4	2	4					2	4	2	4	2	4	2	4	2	4	2	4
Mean Est	477.65	473.42	347.49	354.85					254.67	248.66	14.88	14.03	-4.14	-5.29	-200.53	-199.39	7.91	8.31	-4.94	-5.13
Std Err	17.82	19.24	9.43	6.80					43.65	36.10	4.33	3.62	3.37	3.06	28.19	22.83	2.90	2.13	2.35	1.73
Bias	72.15	67.92	13.49	20.85					-45.33	-51.34	0.88	0.03	2.86	1.71	-0.53	0.61	-0.09	0.31	0.06	-0.13
Truth	405.50	405.50	334.00	334.00					300.00	300.00	14.00	14.00	-7.00	-7.00	-200.00	-200.00	8.00	8.00	-5.00	-5.00
LMEM	σ_yee		σ_yes		σ_wee		σ_wes		γ_1,ee		γ_2,ee		γ_3,ee		γ_1,es		γ_2,es		γ_3,es
Replicates	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4
Mean Est	444.34	446.63	320.41	338.26	255.70	255.85	69.18	71.81	249.50	240.63	14.30	13.67	-4.50	-5.28	-199.27	-198.49	7.91	8.29	-4.91	-5.15
Std Err	16.84	14.22	10.76	7.53	10.74	6.33	2.27	1.56	43.44	37.02	4.25	3.60	3.38	3.04	28.31	22.96	2.91	2.12	2.30	1.71
Bias	38.84	41.13	-13.59	4.26	5.70	5.85	-3.68	-1.05	-50.50	-59.37	0.30	-0.33	2.50	1.72	0.73	1.51	-0.09	0.29	0.09	-0.15
Truth	405.50	405.50	334.00	334.00	250.00	250.00	72.86	72.86	300.00	300.00	14.00	14.00	-7.00	-7.00	-200.00	-200.00	8.00	8.00	-5.00	-5.00
SMEMN	σ_yee		σ_yes		σ_wee		σ_wes		γ_1,ee		γ_2,ee		γ_3,ee		γ_1,es		γ_2,es		γ_3,es
Replicates	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4	2	4
Mean Est	393.69	400.55	313.47	331.79	246.81	248.93	67.61	71.04	293.16	294.61	14.17	14.11	-6.86	-6.78	-200.07	-200.86	8.00	8.04	-4.95	-5.26
Std Err	11.52	8.29	12.00	8.27	8.78	5.79	2.32	1.66	36.16	26.19	3.50	2.42	2.86	2.16	26.86	19.44	2.49	2.06	2.11	1.45
Bias	-11.81	-4.95	-20.53	-2.21	-3.19	-1.07	-5.25	-1.82	-6.84	-5.39	0.17	0.11	0.14	0.22	-0.07	-0.86	0.00	0.04	0.05	-0.26
Truth	405.50	405.50	334.00	334.00	250.00	250.00	72.86	72.86	300.00	300.00	14.00	14.00	-7.00	-7.00	-200.00	-200.00	8.00	8.00	-5.00	-5.00
SMEM		σ_yee		σ_yes		σ_wee		σ_wes		γ_1,ee		γ_2,ee		γ_3,ee		γ_1,es		γ_2,es		γ_3,es
Replicates		4		4		4		4		4		4		4		4		4		4
Mean Est		400.13		331.38		248.94		70.85		297.62		14.16		-7.11		-198.04		8.12		-4.94
Std Err		8.25		8.43		6.05		1.62		26.53		2.72		2.08		18.11		1.85		1.64
Bias		-5.37		-2.62		-1.06		-2.01		-2.38		0.16		-0.11		1.96		0.12		0.06
Truth		405.50		334.00		250.00		72.86		300.00		14.00		-7.00		-200.00		8.00		-5.00