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. 2018 Aug 30;13(8):e0202659. doi: 10.1371/journal.pone.0202659

Table 1. Participants’ characteristics.

Data is expressed as means (SD), with paired Students’ t-test indicating statistical differences between the Sham and the Verum Group. 95% CI = confidence interval, STAI state trait anxiety inventory (with the subscores–T trait and–S state), MDBF multidimensional mood questionnaire, PASA primary appraisal secondary appraisal, HR heart rate HRV heart rate variability.

Verum Acupuncture Sham Laser Students t-test
(n = 12) (n = 13) p-value (95% CI)
Age (yrs) 28.1 (5.5) 27.7 (3.7) 0.836 (-3.3;4.2)
Height (cm) 182.8 (5.1) 181.2 (7.7) 0.549 (-3.8;7.1)
Weight (kg) 84 (10.2) 75.7 (8.5) 0.036 (0.6;16.1)
Test Anxietybaseline cm VAS 7.7 (1.4) 7.2 (1.2) 0.323 (-0.5;1.6)
Perceived Stress in the Experiment (cm VAS) 5.2 (1.7) 5.3 (1.5) 0.943 (-1.5;1.4)
Comparability to Medical State Exam (cm VAS) 3.9 (2.2) 4.1 (2.0) 0.806 (-2.1;1.7)
Cortisolbaseline (nmol/l) 7.7 (3.3) 11 (7.4) 0.158 (-8.1;1.5)
Amylasebaseline (U/ml) 103.4 (86.8) 138.3 (119.8) 0.417 (-122.1;52.3)
Cortisolpeak (T4) (nmol/l) 16.5 (10.5) 19.6 (9.5) 0.451 (-11.4;5.2)
Amylasepeak (T3) (U/ml) 235.5 (225) 280.7 (264.7) 0.652 (-249.3;159.0)
STAI-Tbaseline 33.0 (4.8) 38.8 (6.7) 0.023 (-10.7;-0.88)
MDBFbaseline 33.6 (2.8) 31.2 (9.7) 0.426 (-3.6;8.4)
MDBFpost intervention 34.3 (2.5) 31.1 (9.6) 0.279 (-2.8;9.1)
MDBFpost TSST 31.3 (3.5) 31.4 (3) 0.969 (-2.7;2.6)
STAI-Sbaseline 38 (5.6) 41 (11) 0.406 (-10.3;4.3)
STAI-Spost intervention 32.3 (5.4) 35.8 (8.7) 0.253 (-9.5;2.6)
STAI-Spost TSST 39.9 (7,9) 43.6 (7.4) 0.238 (-10.0;2.6)
PASApost TSST -5.4 (5.6) -3.8 (5.8) 0.479 (-6.4;3.1)
HRbaseline (min-1) 75.8 (12.4) 77.4 (17.7) 0.808 (-14.7;11.6)
HRpost intervention (min-1) 65.7 (11.2) 67.9 (14.2) 0.692 (-12.1;8.9)
HRTSST (min-1) 87.4 (13.9) 91.2 (21.6) 0.619 (-19.5;11.9)
HRVbaseline (ms) 757.1 (270.2) 831.3 (197.6) 0.439 (-268.9;120.5)
HRVpost intervention (ms) 945.4 (163.1) 929.1 (189.7) 0.825 (-135.0;167.6)
HRVTSST (ms) 708 (113.6) 705.4 (184.3) 0.969 (-130.2;135.2)