Table 1. Baseline characteristics of the 149 patients with end-stage renal disease stratified by renal replacement therapy.
| Hemo- dialysis (n = 82) |
Peritoneal dialysis (n = 31) |
Kidney transplantation (n = 36) |
||
|---|---|---|---|---|
| Demographics and medical history | ||||
| Age (y) | 53.3 ±12.2 | 49.8 ±14.2 | 50.4 ±15.1 | |
| Male (%) | 53 (65%) | 21 (68%) | 28 (78%) | |
| BMI (kg/m2) | 26.1 ±5.0 | 24.2 ±3.3 | 24.9 ±3.3 | |
| Systolic blood pressure (mmHg) | 140 ±19 | 134 ±13 | 128 ±13 | |
| Diastolic blood pressure (mmHg) | 77 ±11 | 84 ±12 | 77 ±7 | |
| Diabetes mellitus (%) | 17 (21%) | 1 (3%) | 3 (8%) | |
| Prior cardiovascular disease (%) | 19 (23%) | 6 (19%) | 5 (14%) | |
| Active smoker (%) | 13 (16%) | 5 (16%) | 4 (11%) | |
| History of kidney disease | ||||
| Dialysis vintage (months) | 28 (13–59) | 12 (6–22) | 31 (12–55) | |
| Cause of ESRD (%) | ||||
| • Cystic kidney disease | 9 (11%) | 3 (10%) | 12 (33%) | |
| • Interstitial nephritis | 3 (4%) | 1 (3%) | 1 (3%) | |
| • Glomerulonephritis | 27 (33%) | 7 (23%) | 6 (17%) | |
| • Vascular disease | 15 (18%) | 7 (23%) | 7 (19%) | |
| • Diabetic nephropathy | 9 (11%) | 0 (0%) | 3 (8%) | |
| • Other | 13 (16%) | 7 (23%) | 3 (8%) | |
| • Unknown | 6 (7%) | 6 (19%) | 4 (11%) | |
| Dialysis therapy and kidney function | ||||
| Dialysis therapy | ||||
| • Weekly HD sessions | 3.5 ±0.9 | - | - | |
| • Weekly HD hours | 16.9 ±11.1 | - | - | |
| • Daily PD dwells | - | 4.4 ±0.6 | - | |
| • Daily PD volume (L) | - | 9.3 ±2.1 | - | |
| Kidney function | ||||
| • Residual urine production ≥100mL/24h (%) | 38 (46%) | 21 (68%) | - | |
| • eGFR (mL/min) | - | - | 53 ±20 | |
| Laboratory parameters | ||||
| Calcium (mmol/L) | 2.3 ±0.2 | 2.3 ±0.1 | 2.4 ±0.1 | |
| Albumin (g/L) | 41.5 ±3.2 | 38.7 ±3.1 | 40.3 ±3.2 | |
| Phosphate (mmol/L) | 1.7 ±0.4 | 1.6 ±0.4 | 0.8 ±0.3 | |
| Parathyroid hormone (pmol/L) | 20 (11–43) | 21 (14–42) | 13 (10–27) | |
| C-reactive protein (mg/L) | 3.0 (2.0–5.0) | 1.5 (1.0–6.8) | 3.0 (1.5–5.0) | |
| Total cholesterol (mmol/L) | 4.4 ±1.1 | 5.1 ±1.6 | 4.8 ±1.2 | |
| dp-ucMGP (pmol/L) | 1605 (993–2390) | 1195 (921–1807) | 689 (489–1078) | |
Data are presented as mean ±standard deviation, median (interquartile range) or number (percentage). Abbreviations: BMI: body mass index; ESRD: end-stage renal disease; eGFR: estimated glomerular filtration rate, calculated with the Chronic Kidney Disease-Epidemiology Collaboration equation 2009; dp-ucMGP: desphospho-uncarboxylated matrix Gla-protein.