Fig 1. PD-1 and PD-L1 expression.

Whole blood was labeled to determine PD-1 and PD-L1 subsets. (A) Histogram plots representatives of one healthy individual and one VL-HIV-1⁺ individual. PD-L1⁺ and PD-L1^hi were determined in CD4⁺, in CD8⁺ and CD19⁺ cells. (B) Frequencies of PD-1^hi or PD-L1^hi in CD4⁺, CD8⁺ T and CD19⁺ cells and (C) MFI (median fluorescence intensity) of PD-1 and PD-L1 expression in CD4⁺, CD8⁺ T and CD19⁺ cells. Median [Q1-Q3]; represented. * = p<0.05 when comparing conditions. Each symbol corresponds to an individual.