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. 2018 Aug 20;14(8):e1007153. doi: 10.1371/journal.ppat.1007153

Table 1. Induction of clnR is specific to LL-37-like cathelicidins.

Antimicrobiala Relative clnR expressionb, c
LL-37 530.1 ±110.5
scrambled LL-37 1.7 ± 0.8
mCRAMP 111.4 ± 27.3
SMAP-29 0.7 ± 0.1
Lysozyme 1.1 ± 0.3
Ampicillin 0.9 ± 0.2
Vancomycin 0.9 ± 0.1
Nisin 1.1 ± 0.4
Polymyxin B 1.2 ± 0.2

aConcentrations of antimicrobials used: 2 μg/ml LL-37, 2 μg/ml scrambled LL-37, 2 μg/ml mCRAMP, 0.35 μg/ml SMAP-29, 1 mg/ml lysozyme, 4 μg/ml ampicillin, 0.5 μg/ml vancomycin, 7.5 μg/ml nisin, 200 μg/ml polymyxin B

bRelative expression determined by qRT-PCR and normalized to 630Δerm grown in BHIS without antimicrobials. Values are the mean of three replicates ± standard error of the mean.

cBolded values indicate significant difference (adjusted P value < 0.05) from 630Δerm grown in BHIS without antimicrobials and analyzed by one-way ANOVA and Dunnett’s test for multiple comparisons.