Skip to main content
. 2018 Aug 20;14(8):e1007269. doi: 10.1371/journal.ppat.1007269

Fig 3. Effect of SIVcol Nef on antiviral activity of vertebrate SERINC5 proteins.

Fig 3

Infectious virus yield from HEK293T cells co-transfected with proviral HIV-1 NL4-3 IRES eGFP constructs encoding the indicated nef alleles and pBJ5 SERINC expression or control plasmid. Shown are the mean levels of infectious virus production by the respective IMCs in the presence of transient SERINC5 expression (+SEM; n = 9) relative to those obtained in cells transfected with the control vector (100%). The results were derived from three independent experiments, each using triplicate infection of TZM-bl cells to determine infectious virus yield.