Fig. 1.

The basic viral dynamics model. A) Flow diagram of processes that are tracked in the model, as described in Box 1. B)–C) Example trajectory of viral load (V) and uninfected target cells (CD4⁺ T cells, T) when R₀ > 1 (red) and R₀ < 1 (blue). Graphs were generated by numerically integrating Equation 2 with parameters λ = 100 cells/uL, β = 10⁻⁷ or 0/day/(virus/mL), k = 1000 virus/cell, d_T = 0.1/day, d_I = 1/day, c = 25/day.