Table 3.

Clinical Features

Patients	Mutation	Present age (yrs)	Age of onset (years)	Migraine/headache Features	Frequency	Duration (h)	Cerebellar sign and symptoms	Other clinical features
16/11	del 41–43	17	14	Hemiplegic migraine	5/year	12–48	No cerebellar	No
16/13	del 41–44	42	12	Hemiplegic migraine	2/month	1–2	No cerebellar	Painful paresthesias and mild cognitive deficit
124/11	del 37–47	4	6 (months)	Hemiplegic migraine	2/month	2–3	No cerebellar	Nystagmus, emiplegia, distonia
72/12	del 45–47	19	15	Hemiplegic migraine	6/year	48–72	No cerebellar	Mild cognitive deficit
117/14	del 46–47	39	33	Hemiplegic migraine	2/month	variable	No cerebellar	Muscle pain and fatigue, drop head, loss of deambulation
12/15	del 47	42	23	Hemiplegic migraine	10/year	variable	No cerebellar	No
27/14	del 47	16	20	Hemiplegic migraine	12/year	48–72 h	No cerebellar	No
118/14	del 47	23	17	Hemiplegic migraine	2–3/month	2–3 h	No cerebellar	No
75/13	del 47	13	9	Hemiplegic migraine	2–3/month	variable	No cerebellar	No
187/12	del 12–15	44	12	Episodic ataxia (familiar)	1–2/month	2–3 h	Nystagmus in horizontal and vertical gaze and mild cerebellar signs	Monolateral neurosensory hearing loss
106/16	del 12–15	17	15	Episodic ataxia (familiar)	1–2/week	variable	Multidirectional gaze evoked nystagmus, dysdiadochokinesis, mild difficulty in tandem walking	Congenital stationary night blindness
165/14	del 47	6	1	Episodic ataxia	1/month	variable	No cerebellar	No
195/12	del 47	14	7	MO	2/month	variable	No cerebellar	No
237/12	del 47	60	8	MA	6/year	variable (10 min to 48–72 h)	No cerebellar	Multifocal leukoencephalopathy
80/11	del 47	38	9	MO	2–3/month	variable	No cerebellar	No