Effect of the treatment with chloroform leaf extract (200, 400, 800 mg/kg), ethyl acetate extract (200, 400, 800 mg/kg), essential oil (12.5, 25, 50 mg/kg) and penylbutazone as control (100 mg/kg) on paw edema induced by intradermal injection of carrageenan (1% 0.1 ml) in rats. Zero (time zero) corresponds to baseline measurement of animals performed 24 h before the test. Each group represents the mean of 5 animals, and the vertical lines indicate the SEM. *P < 0.05 and **P < 0.01 compared with control group.