Table 1.

Effects of Mikania cordata on hot plate test in mice.

Treatment	Dose (mg/kg)	Reaction time (sec)
		30 min	60 min	90 min
Control (Vehicle)	–	6.24 ± 0.61	6.28 ± 0.28	6.92 ± 0.34
Morphine	10	13.54 ± 0.49	13.66 ± 0.39**	12.84 ± 0.56**
Essential oil	12.5	7.92 ± 0.52*	7.48 ± 0.45	6.94 ± 0.37*
	25.0	8.86 ± 0.43	9.68 ± 0.19**	9.84 ± 0.10
	50.0	11.82 ± 0.31**	12.3 ± 0.31**	11.14 ± 0.11**
Chloroform extract	200	7.68 ± 0.87	7.72 ± 0.55*	7.08 ± 0.49
	400	9.6 ± 0.96	10.04 ± 0.57**	9.94 ± 0.58*
	800	11.18 ± 0.48*	11.22 ± 0.40**	11.8 ± 0.35**
Ethyl acetate extract	200	7.12 ± 0.26	7.4 ± 0.26	6.98 ± 0.19*
	400	7.64 ± 0.79*	7.72 ± 0.76	7.22 ± 0.75
	800	8.58 ± 0.48	8.94 ± 0.40**	8.1 ± 0.35*

Each value represents the mean (±S.E.M.) of five observations.

^*P < 0.05 and ^**P < 0.01 compared with control group.