Table 3.

Protein interactions involved in S. mansoni life cycle stages that are directly involved in human pathogenesis from the resulting targeted predictions are shown with targeted life cycle stage, the number of predicted interactions for the corresponding life cycle stage and associated human tissues involved in the interaction.

Biological Context Filter Interactions and S. mansoni Life Cycle Stage
Life cycle stage	Correlated Interactions	Life cycle stage-Tissue
Cercariae	460 (460/1345)	1 (skin)
Schistosomula	442 (442/1345)	15
Adult	329 (329/1345)	13
Egg	114 (114/1345)	11

Human tissue expression data were obtained from the GNF Tissue Atlas⁵³ and GO⁵⁶ functional annotation unless noted otherwise.