Table 1.
Elevated gene expression in doxorubicin-resistant A2780DR when compared to A2780 in microarray analysis. Gene name is indicated in the order of fold change of mRNA level of A2780DR to that of A2780
| Rank | Gene name | Description | Fold change |
|---|---|---|---|
| 1 | ABCG2/BCRP | ATP-binding cassette, sub-family G (WHITE), member 2 | 44.714 |
| 2 | ALDH1A1 | Aldehyde dehydrogenase 1 family, member A1 | 29.714 |
| 3 | ELAVL2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 23.836 |
| 4 | CRABP1 | Cellular retinoic acid binding protein 1 | 18.102 |
| 5 | SPP1 | Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 16.595 |
| 6 | SEMA6D | Sema domain, transmembrane domain, and cytoplasmic domain | 13.897 |
| 7 | SLC30A8 | Solute carrier family 30 (zinc transporter), member 8 | 13.777 |
| 8 | DCN | Decorin | 10.450 |
| 9 | LUM | Lumican | 10.310 |
| 10 | NLGN1 | Neuroligin 1 | 10.240 |