Table 4.

The diagnostic value of hepatic fibrosis models for evaluating significant fibrosis, severe fibrosis and cirrhosis.

Fibrosis stage	Variables	Cut-off	AUROC (95% CI)	Se (%)	Sp (%)	PPV (%)	NPV (%)	P-value
≥F2	PSR	1.531	0.777 (0.691–0.849)	84.15	62.86	69.38	79.86	<0.05
	LSR	8.459	0.633 (0.539–0.720)	86.59	37.14	57.94	73.47	<0.05
	APRI	0.437	0.789 (0.704–0.859)	73.17	74.29	74.00	73.47	<0.05
	Frons’ index	7.317	0.674 (0.581–0.757)	64.63	68.57	67.28	65.97	<0.05
	FIB-4 index	1.121	0.704 (0.612–0.785)	89.02	51.43	64.70	82.41	<0.05
	S-index	0.099	0.696 (0.605–0.778)	89.02	54.29	66.07	83.18	<0.05
≥F3	PSR	1.29	0.808 (0.725–0.875)	84.21	70.00	73.73	81.59	<0.05
	LSR	6.169	0.685 (0.593–0.768)	71.93	60.00	64.26	68.13	<0.05
	APRI	0.365	0.739 (0.649–0.815)	89.47	53.33	65.72	83.51	<0.05
	Frons’ index	7.234	0.673 (0.581–0.757)	75.44	56.67	63.52	69.76	<0.05
	FIB-4 index	1.121	0.684 (0.592–0.767)	92.98	38.33	60.12	84.52	<0.05
	S-index	0.099	0.672 (0.579–0.756)	92.98	40.00	60.78	85.07	<0.05
F4	PSR	1.138	0.814 (0.731–0.880)	83.33	67.90	72.19	80.29	<0.05
	LSR	5.377	0.671 (0.578–0.755)	66.67	65.43	65.85	66.25	<0.05
	APRI	0.402	0.711 (0.620–0.791)	88.89	49.38	63.72	81.63	<0.05
	Frons’ index	7.675	0.722 (0.632–0.801)	75.00	64.20	67.69	71.97	<0.05
	FIB-4 index	1.872	0.708 (0.617–0.789)	69.44	70.37	70.09	69.72	<0.05
	S-index	0.175	0.679 (0.587–0.762)	75.00	59.26	64.80	70.33	<0.05