Table 4.
Six selected SNPs lying in the top five annotations with posterior probabilities for causality >0.9
| rs ID | hg19 HGVS identifier | Nearest gene | Chr | Original p-value | Posterior probability | Annotations |
|---|---|---|---|---|---|---|
| rs1884897 | chr20:g.6612832A>G | BMP2 | 20 | 4.57 × 10−13 | >0.99 | DNase |
| rs2213731 | chr1:g.172359815C>A | DNM3-PIGC | 1 | 2.67 × 10−01 | >0.99 | H2AK5ac, DNase |
| rs13083798 | chr3:g.52649748A>G | PBRM1 | 3 | 6.68 × 10−12 | >0.99 | EnhG |
| rs1440372a | chr15:g.67033151T>C | SMAD6 | 15 | 1.34 × 10−10 | 0.99 | H2BK20ac, EnhG, H2AK5ac, DNase |
| rs12608504a | chr19:g.18389135A>G | JUND | 19 | 4.95 × 10−10 | 0.98 | H2AK9ac, H2AK5ac, DNase |
| rs4531856 | chr19:g.18388383C>T | JUND | 19 | 2.49 × 10−06 | 0.97 | DNase |
a Denotes the SNPs that are also original GWA hits