Table 2.
Univariate and multivariate analysis of clinical factors by Cox proportional hazard regression model for overall survival and recurrence-free survival in HCC patients
| Parameter | Overall survival | Recurrence-free survival | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||||||
| HR | P value | 95% CI | HR | P value | 95% CI | HR | P value | 95% CI | HR | P value | 95% CI | |
| Age | 0.845 | 0.701 | 0.358–1.993 | 0.912 | 0.822 | 0.408–2.039 | ||||||
| Gender | 0.561 | 0.320 | 0.180–1.752 | 0.475 | 0.121 | 0.185–1.216 | ||||||
| Tumor size | 6.441 | 0.003* | 1.878–12.092 | 2.418 | 0.251 | 0.536–10.915 | 3.137 | 0.017* | 1.230–7.997 | 0.839 | 0.783 | 0.241–2.924 |
| Serum AFP (mg/L) | 1.177 | 0.731 | 0.463–2.990 | 1.001 | 0.998 | 0.429–2.339 | ||||||
| HBV infection | 1.192 | 0.707 | 0.478–2.975 | 0.996 | 0.993 | 0.410–2.418 | ||||||
| Histologic grade | 6.348 | 0.000* | 2.429–12.591 | 0.375 | 0.229 | 0.076–1.856 | 4.161 | 0.010* | 1.403–12.336 | 0.502 | 0.328 | 0.127–1.993 |
| TNM stage | 5.787 | 0.000* | 2.226–15.046 | 5.854 | 0.002* | 1.905–17.990 | 4.452 | 0.001* | 1.890–10.490 | 3.900 | 0.006* | 1.490–10.240 |
| PVTT | 5.003 | 0.011* | 1.450–7.263 | 4.191 | 0.031* | 1.139–11.416 | 6.040 | 0.000* | 2.474–14.742 | 6.032 | 0.008* | 1.586–12.942 |
| SNHG5 expression | 4.033 | 0.013* | 1.340–11.325 | 4.74 | 0.015* | 1.350–6.640 | 3.548 | 0.013* | 1.311–9.602 | 3.690 | 0.020* | 1.229–11.082 |
*The P values with significance are marked in bold