Figure 5.

Frequencies of major lymphocyte subsets in the peripheral blood of kidney recipients. Recipients who received an ATLG-perfused organ and those who received a saline-perfused organ illustrated similar frequencies of CD3⁺, CD4⁺, CD8⁺ T cells, CD4⁻CD8⁻ T cells, CD19⁺ B cells, and CD56⁺CD3⁻ NK cells. Interestingly, whereas T cell frequencies appeared to decrease in the early postoperative days, there was a significant increase between day 7 post-transplantation (POD 7) and month 6 (p = 0.0078, respectively). Moreover, both patient groups show a significant decrease in CD19⁺ B cells as compared with pre-transplant levels and POD7 (p = 0.001, respectively). ATLG: open boxes, control: filled boxes; data are presented as mean ± SEM; *p < 0.05, **p ≤ 0.01, ***p ≤ 0.001; *, difference within AP; #, difference within CP; ^## < 0.01, ^### < 0.001.