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. 2018 Aug 24;9:1917. doi: 10.3389/fimmu.2018.01917

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Copyright © 2018 Yost, Wang and Marcotrigiano.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different conformations of E2 412–423 peptide in complex with antibodies. The antibody surface is colored yellow, and the peptide is shown as sticks colored according to atom type (light blue, red, orange, and dark blue for carbon, oxygen, sulfur and nitrogen, respectively). E2 peptides are further highlighted in boxes and shown as light blue ribbon structures. (A) β-hairpin peptide in complex with HCV1 antibody (PDB ID: 4DGY). (B) “Open” conformation peptide in complex with neutralizing antibody 3/11 (PDB ID: 4WHY).