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. 2018 Aug 3;94(7):275–304. doi: 10.2183/pjab.94.019

Figure 9.

Figure 9.

Pathology of the globus pallidus and dystonic postures of siblings with Hallervorden–Spatz disease. Pigmentation (A, B, I), demyelination (D), and gliosis (E) in the globus pallidus were marked and localized. Neurospheroids (F, G, H) were observed in the globus pallidus and substantia nigra. CN: caudate nucleus, Pt: putamen, GP: globus pallidus, IC: internal capsule, AC: anterior commissure. Dystonic postures were observed both in the elder (top) and younger (bottom) sisters. (From Yanagisawa et al., 196634)).