Figure 3. MiR-498 was a target of circFADS2.

(A) The schematic showed putative binding sites for circFADS2 and miR-498. (B) Luciferase activity was detected in cells transduced with miR-498 mimics or miR-NC. (C) Si-circFADS2 inhibition up-regulated miR-498 expression in lung cancer cells. (D and E) The expression of miR-498 was markedly reduced and negatively associated with the expression of circFADS2 in NSCLC tissues;*P<0.05