Table 1. Cell lines characteristics.
| Cell line1 | Tumor subtype | ER2 | PR3 | HER2 overexpression4 | Tumor type |
|---|---|---|---|---|---|
| MCF10A | Basal | No | No | No | Non-tumorigenic |
| MCF7 | Luminal | Yes | Yes | No | Adenocarcinoma |
| MDA-MB-231 | Basal | No | No | No | Adenocarcinoma |
| HCC38 | Basal | No | No | No | Ductal carcinoma |
The triple-negative cell lines are defined as invasive breast cancers lacking ER and PR expression and HER2 overexpression or HER2 gene amplification.
1
Table assembled with data from [34].
2
ER positive.
3
PR positive.
4
HER2 overexpression or gene amplification.