Fig. 2.

Berberine regulated hepatic lipid metabolism. (a): HE stained liver tissue of HFD-fed mice (Bar, 50 μm). The view is one from five independent experiments. (b–c): Triacylglycerol (TG) contents in the liver of HFD-fed mice and fasted mice. (d): Gene expressions of Facd and Kct in the liver of HFD-fed mice. (e): Acetyl CoA contents in the liver of HFD-fed mice. (f): Lactate contents in the liver of HFD-fed mice. (g–h): Lactate contents and NAD⁺/NADH ratio in the liver of fasted mice. (BBR, berberine, Met, metformin). Data were expressed as the mean ± SD (n = 5–6). ^⁎p < 0.05 vs. HFD or fasted mice; ^#p < 0.05 vs. chow-fed diet mice.