Figure 1.

Liposome characterization: (A) Schematic drawing of liposomes with encapsulated IGF-1, CNTF, lipopeptide OPP, and lipopeptide PTEN inhibitors (PAP2 or PAP4); (B) liposome size, polydispersity index (PDI), zeta potential, and protein encapsulation efficiency. Liposome diameter and PDI were measured by DLS in HBS, zeta potential was measured in 10 mM HEPES with 5% glucose. Encapsulation efficiency (EE%) of spin-filter purified liposomes was assessed by ELISA (N = 3); (C) CryoTEM images of liposome formulations (scale bar = 100 nm).