Figure 4. Protective activity of four antioxidants against paclitaxel-induced cytotoxicity in differentiated PC12 cells in two independent experiments (Exp 1: A-D; Exp. 2: E-H). Cells were incubated for 48 h with 25 nM paclitaxel in the presence of the indicated concentrations of docosahexaenoic acid (DHA) (A, E), acetyl-L-carnitine hydrochloride (ALC) (B, F), N-acetyl-L-cysteine (NAC) (C, G), or sodium ascorbate (SA) (D, H). Each value represents the mean±S.D. (n=6).