Figure 5. Calculation of alleviation of paclitaxel-induced neurotoxicity by antioxidants. Cells were treated for 48 h with 25 nM paclitaxel in the presence of the indicated concentrations of docosahexaenoic acid (DHA) (A, E), acetyl-L-carnitine hydrochloride (ALC) (B, F), N-acetyl-L-cysteine (NAC) (C,G), or sodium ascorbate (SA) (D, H) and the protective effect of antioxidants was calculated as described in the Materials and Methods section.