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. Author manuscript; available in PMC: 2018 Sep 15.
Published in final edited form as: Exp Cell Res. 2018 Jun 25;370(2):273–282. doi: 10.1016/j.yexcr.2018.06.028

Fig. 7.

Fig. 7.

S1943 NMHC-IIA phosphorylation regulates extravasation in vivo. (A) Pan-cytoker- atin stained lung sections from SCID mice injected with MDA-MB-231 cells expressing wild- type, S1943A or S1943E NMHC-IIA six weeks after injection of tumor cells. Arrowheads indicate metastatic foci. Bar = 200 μm. (B) The number and percent area of metastases per lung section six weeks after injection of tumor cells. Data represent the mean ± SEM from two independent experiments with a total of 15, 13, and 14 mice for wild-type, SI943A, or S1943E NMHC-IIA cells, respectively. Statistical analyses were performed using ANOVA. (C) The percent area of metastases per lung section eight weeks after injection of tumor cells. Data represent the mean ± SEM from 8 mice each for wild-type, S1943A or S1943E NMHC-IIA cells, respectively. Statistical analyses were performed using ANOVA.