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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Toxicol Sci. 2017 Nov 1;160(1):15–29. doi: 10.1093/toxsci/kfx153

Figure 1. Labeling index (LI) for the proliferation marker Ki67 in the livers of mice treated with A4, EE, or PRED.

Figure 1.

Figure 1.

Figure 1.

Figure 1.

Ki67 LI is shown for large cells (grey), small cells (white), and all cells combined (black) after 7 days (A-C) and 28 days (D) of exposure. Significance is indicated by *p < 0.05 and **p < 0.01 compared to the respective control (Con) group. The 0 mg/kg A4 group indicates gavage control.