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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: J Autoimmun. 2018 Jul 13;93:76–88. doi: 10.1016/j.jaut.2018.06.006

Figure 4.

Figure 4.

CD80/CD86 costimulatory marker expression in splenocytes isolated from EAE mice on day 25 following in vivo treatment with groups 3–9 and 72h ex vivo antigen rechallenge +/− PLP (25 μM), determined by flow cytometry: A/B) B cells (CD19+), C/D) ABCs (CD 19+B220+CD 11c+), and E/F) DCs (CD11c+). Data represent mean ± SD (n=3). Statistical significance compared to PBS negative control was determined by two-way ANOVA followed by Dunnett’s post hoc test; statistical significance between +/− PLP (underlined) was determined by two-way ANOVA followed by Sidak’s post hoc test (*p<0.05, **p<0.01, #p<0.001, ##p<0.0001). MFI = mean fluorescent intensity.