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. 2018 Aug 31;6:85. doi: 10.1186/s40478-018-0588-z

Fig. 1.

Fig. 1

Swimmer plot depicting CSF sample collections for each patient. Each bar represents one subject included in the study. The blue crosses represent CSF collections. Surgery is indicated by the red square. Grey circles represent the initial diagnosis. The X-axis represents months. For some patients with metastatic disease (i.e., breast and lung cancer) the initial diagnosis of the systemic malignancy occured many months before the development of CNS disease