Table 1.
FEV1 and Sex Difference in Breathlessness
| Models, All Adjusted for Confounders* | Sex Difference in mMRC Breathlessness Scale Score, for Women vs. Men [OR (95% CI)] |
|---|---|
| All participants (N = 10,223) | |
| Without any FEV1 measure | 1.75 (1.62–1.90) |
| With FEV1% predicted | 1.72 (1.59–1.86) |
| With FEV1, L | 0.93 (0.84–1.03) |
| Participants with FEV1 ≥ 80% predicted (n = 5,288) | |
| Without any FEV1 measure | 1.95 (1.73–2.19) |
| With FEV1, L | 1.11 (0.94–1.31) |
| Participants with FEV1 < 80% predicted (n = 4,935) | |
| Without any FEV1 measure | 1.57 (1.41–1.75) |
| With FEV1, L | 0.84 (0.73–0.95) |
Definition of abbreviations: CI = confidence interval; mMRC = modified Medical Research Council; OR = odds ratio.
*
All models were adjusted for age, body mass index, pack-years of smoking, current smoking, FEV1/FVC, asthma, chronic obstructive pulmonary disease or emphysema, chronic bronchitis, heart failure, cardiovascular disease, and diabetes mellitus.