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. 2018 Mar 19;12(7):E281–E297. doi: 10.5489/cuaj.5246

Table 2.

Change in pathology report and treatment based on pathological second opinion from a GU-focused pathologist

n (%)
Pathological changes on review
 Stage 115/1191 (9.7)
 Grade 62/1191 (5.2)
 Presence or absence of CIS 34/1191 (2.9)
 Presence of lymphovascular invasion 35/620 (5.6)
 Mixed, variant, or nonurothelial histology 114/212 (53.8)
Treatment alterations
 Any treatment alteration 182/1191 (15.3)
 Major alteration in treatment 141/1191 (11.8)
 Change for radical cystectomy 82/1191 (6.8)
 Change in primary tumour type 38/1191 (3.2)
 Change in systemic chemotherapy regimen 21/1191 (1.8)
 Minor alteration in treatment 41/1191 (3.4)

CIS: carcinoma in situ; GU: genitourinary.