Table 4.
Deviation from Hardy-Weinberg equilibrium in the ADAM33 gene in patients from southwestern Iran with asthma and healthy controls
|
ADAm33
SNPs |
Position | Alleles |
HWE
|
|||||
|---|---|---|---|---|---|---|---|---|
|
Patients
|
Controls
|
|||||||
| Obs HET | Pred HET | P-value | Obs HET | Pred HET | P-value | |||
| T+1 | 3669480 | G:A | 0.447 | 0.388 | 0.1009 | 0.336 | 0.337 | 1.0000 |
| T1 | 3669587 | A:G | 0.467 | 0.397 | 0.0509 | 0.497 | 0.422 | 0.0474 |
| S1 | 3671118 | G:A | 0.333 | 0.287 | 0.0713 | 0.289 | 0.247 | 0.0574 |
| F+1 | 3674438 | T:C | 0.8 | 0.485 | <0.00001 | 0.792 | 0.488 | <0.00001 |
Obs HET: observed heterozygosity; Pred HET: predicted heterozygosity