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The effects of different doses (50, 150, and 300 mg/kg) of troxerutin on the anxiety-like behaviors in the open field test: (a) time spent in the center, (b) the number of entrances into the center, and (c) line entrance number. Data are expressed as means ± SEM (n=8); *P<0.05, **P<0.01, *** P<0.001 vs. control, # P<0.05, ## P<0.01 vs. saline group. TRX: troxerutin
