Table 1.
Treatment and Dose | Plasma | Liver | Kidney |
---|---|---|---|
Cholesterol (mmol/L) | |||
Control | 1.33±0.25 | 0.70±0.42 | 0.15±0.02 |
Vitamin C (10 mg/kg) | 1.25±0.36 | 0.59±0.02 | 0.20±0.11 |
ETD (500 mg/kg) | 1.38±0.25 | 0.64±0.27 | 0.14±0.07 |
ETD (1000 mg/kg) | 1.35±0.29 | 0.67±0.18 | 0.13±0.02 |
ETD (1500 mg/kg) | 1.18±0.49* | 0.63±0.31 | 0.17±0.09 |
High-density lipoprotein (mmol/L) | |||
Control | 1.12±0.27 | 0.12±0.07 | 0.05±0.04 |
Vitamin C (10 mg/kg) | 1.69±0.16* | 0.16±0.02 | 0.09±0.09 |
ETD (500 mg/kg) | 1.62±0.20* | 0.22±0.09 | 0.04±0.02 |
ETD (1000 mg/kg) | 1.64±0.22* | 0.18±0.02 | 0.05±0.02 |
ETD (1500 mg/kg) | 1.73±0.11* | 0.15±0.07 | 0.07±0.04 |
Triglyceride (mmol/L) | |||
Control | 2.32±0.20 | 1.27±0.20 | 0.25±0.31 |
Vitamin C (10 mg/kg) | 2.50±0.36 | 1.24±0.56 | 0.25±0.27 |
ETD (500 mg/kg) | 2.36±0.25 | 1.18±0.45 | 0.22±0.11 |
ETD (1000 mg/kg) | 2.28±0.38 | 1.24±0.25 | 0.19±0.16 |
ETD (1500 mg/kg) | 2.66±0.27 | 1.13±0.27 | 0.16±0.07 |
Low-density lipoprotein (mmol/L) | |||
Control | 0.62±0.40 | 0.54±0.51 | 0.11±0.11 |
Vitamin C (10 mg/kg) | 0.43±0.34 | 0.46±0.45 | 0.08±0.07 |
ETD (500 mg/kg) | 0.53±0.25 | 0.56±0.27 | 0.09±0.04 |
ETD (1000 mg/kg) | 0.47±0.18 | 0.49±0.34 | 0.11±0.11 |
ETD (1500 mg/kg) | 0.48±0.11 | 0.53±0.42 | 0.13±0.11 |
Data are expressed as mean ± S.D. (n = 5). Values denoted with (*) down a column are significantly different at p< 0.05 when compared with control group