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. Author manuscript; available in PMC: 2018 Aug 31.
Published in final edited form as: Expert Rev Proteomics. 2017 Sep 20;14(10):905–915. doi: 10.1080/14789450.2017.1374860

Figure 1. Overview of composition and function of selected chromatin remodeling complexes.

Figure 1.

General architectural representations of chromatin remodeling complexes studied using proteomics technologies is shown. These complexes include the Swr1 complex, the NuRD complex, the SAGA complex, the Sin3 complex, the Swi/Snf complex, the Tip60 complex, and the Ino80 complex. A generalized representation of the histone octamer is shown in yellow and green and the general biological function of each complex is shown. HDAC 1 and HDAC2 are highlighted in pink since they are parts of multiple complexes. The drawing is not to scale and only reflects relative sizes of the subunits. A single schematic nucleosome is shown (yellow), an acetyl group is represented by Ac and ubiquitin is represented by Ub.