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. Author manuscript; available in PMC: 2018 Aug 31.
Published in final edited form as: Nature. 2018 Mar 5;556(7699):126–129. doi: 10.1038/nature26156

Figure 1. Structure of the early nucleolar pre-60S particle.

Figure 1

a, Composite cryo-EM density map of state 2, consisting of 25S rRNA domains I and II (3.4 Å) and VI (3.7 Å) (low-pass filtered to 5 Å), and associated proteins. b, Corresponding near-atomic model of state 2 with ribosome assembly factors and 25S rRNA domains labelled and colour-coded. Ribosomal proteins are shown in grey.