a, Two views of the nucleolar pre-60S particle state 2 model, with Diamond–Blackfan anaemia-associated ribosomal proteins shown in surface representation. b, Rpl15 is located between the 5.8S-domain I duplex and a domain I–domain II interface. c, Rpl33 (Rpl35 in Homo sapiens) binds at the junction of domains I, II and VI in the 25S rRNA. d, Rpl26 associates with the domain I–5.8S rRNA interface and additionally inserts its N terminus (N) between domain I and domain II.