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Effects of insulin and S961 on insulin receptor (IR-A and IR-B) mRNA expression in breast cancer cells. The mRNA levels of insulin receptor isoforms in MCF-7 cells (A) MDA-MB-231 cells (B) and T47D cells (C) were measured by quantitative PCR analysis. All data are represented as means±standard deviation, n=3, P*< 0.05, **<0.01 and ***<0.001 vs control.
