Table 1:
Composition of the overexpression library
| 21 | 22 | 23 | 24 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Insertion sequences and phages | 2 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 |
| Intermediary metabolism and respiration | 31 | 38 | 45 | 21 | 31 | 14 | 14 | 18 | 29 | 0 | 3 | 4 | 4 | 8 | 11 | 88 | 85 | 87 | 88 | 88 | 707 |
| Information pathways | 17 | 8 | 10 | 8 | 25 | 49 | 42 | 48 | 20 | 4 | 0 | 0 | 0 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 240 |
| Cell wall and cell processes | 12 | 22 | 12 | 21 | 14 | 9 | 12 | 11 | 14 | 1 | 3 | 4 | 1 | 5 | 6 | 0 | 1 | 0 | 0 | 0 | 148 |
| Conserved hypothetical | 17 | 6 | 8 | 2 | 8 | 8 | 7 | 3 | 8 | 1 | 2 | 0 | 2 | 1 | 2 | 0 | 2 | 0 | 0 | 0 | 77 |
| Virulence, detoxification, adaptation | 3 | 6 | 3 | 1 | 2 | 1 | 1 | 3 | 2 | 33 | 23 | 35 | 24 | 29 | 22 | 0 | 0 | 0 | 0 | 0 | 188 |
| Lipid metabolism | 3 | 7 | 8 | 7 | 3 | 2 | 5 | 1 | 7 | 26 | 31 | 24 | 38 | 22 | 20 | 0 | 0 | 0 | 0 | 0 | 204 |
| PE/PPE | 1 | 0 | 0 | 1 | 1 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 |
| Regulatory proteins | 2 | 1 | 1 | 1 | 4 | 3 | 3 | 4 | 4 | 23 | 26 | 21 | 18 | 20 | 21 | 0 | 0 | 0 | 0 | 0 | 152 |
| Total | 88 | 88 | 88 | 62 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 88 | 87 | 88 | 88 | 1733 |
Gene classifications were taken from taken from Tuberculist (now Mycobrowser) https://mycobrowser.epfl.ch. The composition of each plate (POET 21–41) is given.