Table 1.
Injection with Dex and/or propofol did not affect arterial blood gas
| Group | pH | PaO2 (mmHg) |
PaCO2 (mmHg) |
HCO3− (mmol/L) |
|---|---|---|---|---|
| NS | 7.30±0.02 | 92.6±5.6 | 44.3±4.5 | 23.7±2.4 |
| P | 7.28±0.02 | 89.2±8.4 | 50.4±5.1 | 22.5±2.4 |
| PD25 | 7.29±0.03 | 89.0±9.4 | 48.7±5.7 | 23.6±2.6 |
| PD50 | 7.28±0.02 | 91.8±7.4 | 50.9±6.3 | 23.1±3.4 |
| PD75 | 7.28±0.03 | 89.2±8.2 | 46.6±5.3 | 23.1±3.4 |
| LPD | 7.30±0.02 | 89.6±7.8 | 49.4±4.5 | 22.8±2.7 |
| TPD | 7.29±0.03 | 89.0±7.5 | 48.9±2.9 | 22.8±2.8 |
| F | 7.30±0.02 | 91.4±8.0 | 44.9±4.7 | 23.8±2.9 |
| DS1 | 7.30±0.02 | 91.4±8.0 | 45.1±4.5 | 24.6±3.1 |
| DS2 | 7.29±0.01 | 94.0±5.7 | 44.4±4.8 | 23.9±3.0 |
| Dex | 7.30±0.02 | 92.4±7.8 | 43.3±5.6 | 23.5±2.9 |
| L | 7.30±0.02 | 89.60±6.8 | 46.6±5.8 | 22.9±2.6 |
| T | 7.30±0.02 | 90.6±7.1 | 45.9±4.6 | 22.8±2.5 |
Notes: NS group: saline; P group: propofol; PD25, PD50 and PD75 groups: pretreatment with Dex, injection with propofol; LPD group: pretreatment with LY294002 and Dex, injection with propofol; TPD group: pretreatment with TDZD-8 and Dex, injection with propofol; F group: intralipid; DS1 group: intracerebroventricular injection with DMSO; DS2 group: intraperitoneal injection with DMSO; Dex group: Dex; L group: intracerebroventricular injection with LY294002; T group: TDZD-8. Results are presented as the mean±SEM (n=5 per group).
Abbreviations: Dex, dexmedetomidine; DMSO, dimethyl sulfoxide; SEM, standard error of the mean.