Table 3.

The frequencies of IGF2BP2 rs1470579 A>C, rs4402960 G>T and IGFBP3 rs2270628 C>T, rs3110697 G>A and rs6953668 G>A polymorphisms in different NSCLC subgroups

Genotype	NSCLC cases (n=521)		Adenocarcinoma (n=415)		Non-adenocarcinoma (n=106)		Controls (n=1,030)
	n	%	n	%	n	%	n	%
IGF2BP2 rs1470579 A>C
AA	302	58.54	241	58.07	61	57.55	593	57.63
AC	187	35.89	148	35.66	39	36.79	350	34.01
CC	32	6.14	26	6.27	6	5.66	86	8.36
C allele	251	24.09	200	24.10	51	24.06	522	25.36
IGF2BP2 rs4402960 G>T
GG	306	58.73	244	58.80	62	58.49	603	58.60
GT	185	35.51	146	35.18	39	36.79	344	33.43
TT	30	5.76	25	6.03	5	4.72	82	7.97
T allele	245	23.51	196	23.61	49	23.11	508	24.68
IGFBP3 rs2270628 C>T
CC	334	64.11	273	65.78	61	57.55	670	65.11
CT	163	31.29	122	29.40	41	38.68	318	30.90
TT	24	4.61	20	4.82	4	3.77	41	3.98
T allele	211	20.25	162	19.52	49	23.11	400	19.44
IGFBP3 rs3110697 G>A
GG	286	54.89	235	56.63	51	48.11	578	56.17
GA	190	36.47	142	34.22	48	45.28	373	36.25
AA	45	8.64	38	9.16	7	6.60	78	7.58
A allele	280	26.87	218	26.27	62	29.25	529	25.70
IGFBP3 rs6953668 G>A
GG	466	89.44	375	90.36	91	85.85	920	89.49
GA	53	10.17	39	9.40	14	13.21	104	10.12
AA	2	0.38	1	0.24	1	0.94	4	0.39
A allele	57	5.47	41	4.94	16	7.55	112	5.45

Abbreviation: NSCLC, non-small-cell lung cancer.