Table 1.

Clinicopathological characteristics of GEO datasets used in this study

GEO datasets	Clinicopathological characteristics
GSE41258	This study consisted of patients who presented at Memorial Sloan-Kettering Cancer Center with a colonic neoplasm between 1992 and 2004. Biological specimens used in this study included primary colon adenocarcinomas, adenomas, metastasis, and corresponding normal mucosae.
GSE17536	A total of 55 colorectal cancer patients from Vanderbilt Medical Center (VMC) were used as the training dataset and 177 patients from the Moffitt Cancer Center were used as the independent dataset.
GSE33113	Primary tumor resections from 90 AJCC stage II CRC patients, that underwent intentionally curative surgery, and matching normal colon tissue from six of these patients were included in the study (1997–2006 [AMC-AJCCII-90]). Extensive medical records were kept from these patients and long-term clinical follow-up is available for the large majority.

Abbreviations: AJCC, American Joint Committee on Cancer; CRC, colorectal cancer; AMC, Academic Medical Center.