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Significant results from testing between genotypes for outcomes of pharmacokinetics
| Outcome | Direction | P value | Q value |
|---|---|---|---|
| Group 1 vs. group 3 (143E allele) | |||
| AUC d‐MPH | Group 3 higher | 0.000454 | 0.003630 |
| Half‐life d‐MPH | Group 3 higher | 0.000982 | 0.007860 |
| Cmax d‐MPH | Group 3 higher | 0.007112 | 0.056892 |
AUC, area under the curve; Cmax, peak plasma concentration; MPH, methylphenidate.
