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. 2018 Aug 31;13(8):e0203064. doi: 10.1371/journal.pone.0203064

Table 6. Cytotoxic activities of selected Trametes spp. basidiocarp and mycelium extracts and commercial cytostatics.

Species Extract IC50 [μg mL-1]
HeLa LS174 A549 MRC5
Trametes gibbosa basidiocarps 193.53 ± 8.91 Ba >200.00 A >200.00 A >200.00 A
mycelium >200.00 A >200.00 A >200.00 A >200.00 A
Trametes hirsuta basidiocarps 116.13 ± 3.14 C 158.46 ± 37.15 B 177.66 ± 20.17 B 175.70 ± 1.45 B
mycelium 21.01 ± 1.95 E 45.75 ± 0.02 D 57.94 ± 5.08 C 145.17 ± 6.48 C
Trametes versicolor basidiocarps 168.54 ± 28.90 B >200.00 A >200.00 A >200.00 A
mycelium 42.40 ± 0.74 D 86.12 ± 12.34 C 65.57 ± 7.75 C 77.37 ± 0.82 D
cis-DDP* 2.10 ± 0.20 F 5.54 ± 1.03 E 11.92 ± 2.19 D 14.44 ± 1.90 E
Doxorubicin* 0.62 ± 0.30 G 3.78 ± 0.49 F 0.24 ± 0.02 E 0.46 ± 0.18 F

a Means with different letters within a column are significantly different (P<0.01)

*Commercial cytostatic