Table 2. Linear regression models were used to find Pearson correlation coefficients and part correlations, with adjustments for age as a covariate, between magnetic-resonance imaging outcomes of central adiposity and biomarkers of cardiometabolic disease.
| Pearson correlation coefficients (r) | Part correlation coefficients (r), accounting for age | |||||||
|---|---|---|---|---|---|---|---|---|
| VATCSA (cm2) | VAT volume (cm3) | CSA/Total | VAT:SAT | VATCSA (cm2) | VAT volume (cm3) | CSA/Total | VAT:SAT | |
| Blood Pressure | ||||||||
| SYS | 0.01 | 0.08 | -0.10 | -0.15 | -0.18 | -0.05 | -0.35 | -0.25 |
| DIA | 0.32 | 0.33 | 0.34 | 0.37 | 0.08 | 0.11 | 0.11 | 0.14 |
| Whole body physiology | ||||||||
| VO2 peak | -0.62† | -0.60† | -0.64† | -0.51 | -0.07 | -0.09 | -0.08 | 0.00 |
| BMR | -0.37 | -0.30 | -0.46† | -0.44 | -0.22 | -0.10 | -0.37 | -0.31 |
| Lipid profile | ||||||||
| LDL-C | 0.05 | 0.02 | -0.05 | -0.28 | 0.19 | 0.13 | 0.03 | -0.22 |
| HDL-C | -0.39 | -0.38 | -0.49† | -0.60* | -0.21 | -0.20 | -0.40 | -0.39† |
| Non-HDL | 0.29 | 0.28 | 0.21 | 0.03 | 0.28 | 0.24 | 0.13 | -0.09 |
| Total cholesterol | 0.17 | 0.16 | 0.06 | -0.14 | 0.21 | 0.18 | 0.01 | -0.19 |
| TG+ | 0.51† | 0.50† | 0.59* | 0.57* | 0.17 | 0.15 | 0.30 | 0.25 |
| FFA | 0.33 | 0.35 | 0.31 | 0.22 | 0.45 | 0.44 | 0.41 | 0.16 |
| Carbohydrate Profile | ||||||||
| HbA1c | 0.49† | 0.47† | 0.56† | 0.69* | 0.19 | 0.16 | 0.31 | 0.40† |
| Si+ | -0.53† | -0.55† | -0.66* | -0.56† | -0.27 | -0.31 | -0.51† | -0.24 |
| Sg+ | -0.08 | -0.07 | -0.23 | -0.42 | 0.17 | 0.13 | -0.10 | -0.27 |
| Inflammatory markers | ||||||||
| CRP+ | 0.20 | 0.23 | 0.28 | -0.01 | 0.11 | 0.17 | 0.24 | -0.13 |
| TNF-α+ | 0.30 | 0.33 | 0.30 | 0.13 | 0.46† | 0.48† | 0.44 | 0.10 |
| IL-6- | 0.04 | 0.10 | 0.09 | 0.07 | 0.16 | 0.25 | 0.23 | 0.12 |
Basal metabolic rate; BMR, c-reactive protein; CRP, cross-sectional area; CSA, diastolic blood pressure; DIA, free fatty acid; FFA, glucose effectiveness; Sg, glycated hemoglobin; HbA1c, high-density lipoprotein cholesterol; HDL-C, insulin sensitivity; Si, interleukin-6; IL-6, low-density lipoprotein cholesterol; LDL-C, peak oxygen uptake; VO2 peak, triglycerides; TG, tumor necrosis factor alpha; TNF-α, subcutaneous adipose tissue; SAT, systolic blood pressure; SYS, Visceral adipose tissue cross-sectional area; VATCSA.
+ positive skew (data was log transformed prior to analysis)
- negative skew (data was reflected and log transformed prior to analysis).
†P < 0.05
*P < 0.01.