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Second Generation Ultrasound Contrast Agents approved for use in the United States[14]
| Agent | Manufacturer | Gas Core | Shell |
|---|---|---|---|
| Optison | GE Healthcare (Princeton, NJ) | Octafluoropropane | Albumin |
| Definity | Lantheus Medical Imaging (N. Billerica, MA) | Octafluoropropane | Phospholipid |
| Lumason | Bracco Diagnostics (Monroe Township, NJ) | Sulfur Hexafluoride | Phospholipid |
