Table 2.
Summary of endpoint data from longitudinal study of TgMISIIR-TAg;Nedd9+/+ and TgMISIIR-TAg;Nedd9−/− mice.
| MISIIR-TAg;Nedd9−/− mouse ID | Age at death (days) | Ovary (tumor) volume* | Ascites | Visible spread | Microscopic spread |
|---|---|---|---|---|---|
| 43 | 145 | 756.1 | − | + | + |
| 49 | 153 | 946.0 | − | − | + |
| 55 | 148 | 1208.9 | − | − | + |
| 63A | 182 | 1581.6 | + | + | + |
| 70 | 192 | 2284.1 | + | + | + |
| 94 | 130 | 122.7 | − | − | + |
| 115 | 141 | 691.4 | + | + | + |
| 128 | 151 | 35.4 | − | + | + |
| 129 | 163 | 1843.6 | + | + | + |
| 136 | 138 | 1255.0 | − | + | + |
| 143 | 188 | 730.3 | − | + | + |
| 144 | 163 | 1765.5 | + | + | + |
| 145 | 188 | 1889.7 | + | + | + |
| 146 | 193 | 530.5 | + | − | + |
| 156 | 138 | 1866.8 | + | + | + |
| 157 | 150 | 181.9 | n/a | n/a | n/a |
| 158 | 200 | 1748.6 | − | − | + |
| 159 | 158 | 1289.0 | − | + | + |
| 166 | 138 | 1680.5 | + | + | + |
| 168 | 150 | 1912.2 | − | + | + |
| 173 | 118 | 2563.2 | − | − | + |
| 192 | 183 | 2717.3 | + | − | + |
| 194 | 191 | 978.2 | + | + | + |
| 195 | 204 | 840.5 | − | − | + |
| 197 | 178 | 25.0 | − | − | + |
| 210 | 156 | 33.9 | n/a | n/a | n/a |
| 212 | 175 | 2870.9 | + | + | + |
|
| |||||
| MISIIR-TAg;Nedd9+/+ mouse ID | Age at death (days) | Ovary (tumor) volume | Ascites | Visible spread | Microscopic spread |
|
| |||||
| 7272 | 155 | 1237.0 | no | + | + |
| 7283 | 175 | 1615.8 | − | − | + |
| 7286 | 158 | 642.6 | − | − | + |
| 7429 | 186 | 947.4 | + | + | + |
| 7431 | 181 | 1635.0 | + | + | + |
| 7452 | 170 | 1015.1 | − | − | + |
| 7473 | 159 | 3125.8 | + | + | + |
| 7494 | 168 | 783.1 | − | + | + |
| 7496 | 128 | 33.3 | + | + | + |
| 7507 | 149 | 1527.9 | − | + | + |
| 7509 | 135 | 1921.6 | − | + | + |
| 7510 | 128 | 658.2 | + | + | + |
| 7516 | 209 | 2267.0 | + | + | + |
| 7518 | 136 | 1555.9 | + | − | + |
| 7523 | 212 | 426.4 | + | + | + |
| 7524 | 154 | 2225.6 | n/a | n/a | n/a |
| 7540 | 146 | 957.8 | − | − | + |
| 7547 | 157 | 1973.7 | − | + | + |
| 7549 | 183 | 1577.9 | + | + | + |
| 7555 | 132 | 1853.4 | − | + | + |
| 7575 | 137 | 889.3 | − | − | + |
| 7577 | 207 | 1356.4 | + | − | + |
| 7793 | 134 | 1424.4 | + | + | + |
| 7859 | 140 | 1227.3 | − | − | + |
| 7865 | 149 | 1725.9 | − | − | + |
| 7272 | 155 | 1237.0 | n/a | n/a | n/a |
| 7283 | 175 | 1615.8 | + | + | + |
| 7286 | 158 | 642.6 | − | + | + |
| 7429 | 186 | 947.4 | − | − | + |
| 7431 | 181 | 1635.0 | − | − | + |
*
measurement at last MRI scan
n/a = tissue not available for evaluation