Trabecular parameters and duration of type 2 diabetes (T2D). Values were compared between controls (n=50), early T2D (T2D duration <10 years; n=22), and late T2D (T2D duration ≥10 years; n=20). In comparison to controls, trabecular bone volume fraction, trabecular volumetric BMD, trabecular plate number density, and plate–plate junction density were increased in early T2D, whereas trabecular rod length was decreased (A). Cortical volumetric BMD, cortical porosity, and cortical load fraction at the distal site (not shown) did not differ between T2D subjects with greater or less than 10 years of disease duration, whereas cortical load fraction (at the proximal site) was decreased and stiffness was increased (B). There was no difference between late T2D and controls in any of the parameters. Values are mean±SD.