Fig. 7.

Production of secreted proteins in primary airway epithelial cells. Primary human nasal epithelial cells were transduced with rSIV.F/HN-expressing hAAT (rSIV.F/HN-hCEF-sohAAT, 1e6 transduction units (TU)/well) or hFVIII (rSIV.F/HN-CMV-FVIII-N6, 1e6 TU/well) or treated with D-PBS (negative control) (n = 6/group). Human AAT (a) and human FVIII (b) were quantified 24 h post transduction. Each symbol represents an individual sample. Horizontal bars indicate the group median. ** = p < 0.01 compared with negative control using analysis of variance followed by a Bonferroni post hoc test