Table 2.
PRS correlation with clinical variable during the baseline and the follow-up
| Time | Clinical variable | N | B | p-value | |
|---|---|---|---|---|---|
| Baseline (antipsychotic naive FEP) | CGI | 50 | 72.8 | 0.8436 | |
| a−GAF | 48 | 436.1 | 0.0030 | ||
| aCDSS total | 51 | 1042.3 | 0.0039 | ||
| PANSS total | 53 | 38.1 | 0.6390 | ||
| aPANSS positive | 53 | 400.0 | 0.0278 | ||
| PANSS negative | 53 | −205.6 | 0.3048 | ||
| PANSS general psychopathology | 53 | −20.2 | 0.8886 | ||
| Five-factor model21 | PANSS negative | 53 | −168.2 | 0.2655 | |
| PANSS disorganization/cognition | 53 | −32.9 | 0.8281 | ||
| bPANSS excitement | 53 | 566.7 | 0.0003 | ||
| PANSS positive | 53 | 27.1 | 0.8382 | ||
| PANSS depression/anxiety | 53 | −112.8 | 0.4761 | ||
| Follow-up (9 weeks treated with risperidone) | CGI | 51 | −137.4 | 0.7588 | |
| −GAF | 53 | −132.8 | 0.2281 | ||
| bCDSS total | 53 | −1800.2 | 0.0004 | ||
| PANSS total | 54 | −113.4 | 0.2215 | ||
| PANSS positive | 56 | 277.3 | 0.3141 | ||
| PANSS negative | 56 | −358.3 | 0.0894 | ||
| PANSS general psychopathology | 54 | −287.9 | 0.1140 | ||
| Five-factor model21 | PANSS negative | 56 | −180.6 | 0.2329 | |
| PANSS disorganization/cognition | 56 | −75.8 | 0.6608 | ||
| PANSS excitement | 56 | 216.4 | 0.3048 | ||
| PANSS positive | 56 | 10.0 | 0.9522 | ||
| bPANSS depression/anxiety | 55 | −575.0 | 0.0013 | ||
PANSS Positive and Negative Syndrome Scale, CGI Clinical Global Impression Scale, GAF Global Assessment of Functioning Scale, CDSS Calgary Depression Scale for Schizophrenia
aSignificant p-values without Bonferroni correction
bSignificant p-values with Bonferroni correction