Table 4.
Association between the statistically significant clinical variables with PRS splitting the FEP patients into FEP subtypes according to the follow-up diagnosis
| Subtype | Clinical variable | Timepoint | N | B | p-value |
|---|---|---|---|---|---|
| Schizophreniform | a−GAF | Baseline | 9 | −1449.1 | 0.00013 |
| bCDSS | Baseline | 9 | 2660.0 | 0.03594 | |
| CDSS | Follow-up | 10 | −2323.7 | 0.20033 | |
| aPANSS excitement | Baseline | 11 | 1393.3 | 0.00009 | |
| PANSS depression/anxiety | Follow-up | 10 | −622.3 | 0.15126 | |
| bΔPANSS excitement | Baseline - follow-up | 11 | 877.8 | 0.02002 | |
| ΔCDSS | Baseline - follow-up | 9 | 497.4 | 0.30954 | |
| Schizophrenia only | −GAF | Baseline | 27 | 300.3 | 0.21538 |
| bCDSS | Baseline | 29 | 1746.1 | 0.00217 | |
| aCDSS | Follow-up | 27 | −3739.3 | 0.00009 | |
| PANSS excitement | Baseline | 29 | 206.5 | 0.39645 | |
| aPANSS depression/anxiety | Follow-up | 29 | −1286.2 | 0.00002 | |
| ΔPANSS excitement | Baseline - follow-up | 29 | 324.9 | 0.19858 | |
| aΔCDSS | Baseline - follow-up | 27 | 1358.7 | 0.00002 |
aSignificant p-values with Bonferroni correction
bSignificant p-values without Bonferroni correction